PhD vacancy

Within the framework of our recently obtained Ammodo Award, we have a vacancy for a PhD position in organic synthesis, entitled “total synthesis of membrane components of M. tuberculosis.” In an ongoing collaboration with molecular tuberculosis-experts and immunologists we identify, characterize and synthesize new (membrane) components of the bacterial pathogen M. tuberculosis. These compounds have shown to be important for pathogenesis and virulence and are highly interesting from a molecular structure point of view. In parallel, we study how to translate fundamental findings in organic synthesis, such as in photochemistry and electrochemistry, into the synthesis of complex natural products. This is essential not only for the identification of these compounds but also for their production as adjuvants, in future diagnostics and vaccines.

Job description

You will design and execute synthesis routes to new molecules from M. tuberculosis, discovered within the “Lipidomics Team”. These compounds will be used in immunology studies by our collaborators. You will be trained in organic synthesis and catalysis, including NMR spectroscopy and chromatography, in photoredox chemistry and in electrosynthesis. We stimulate initiative, and creativity of our students. Additionally, you will be involved in teaching, by supervising tutorials and bachelor/master theses.

Profile

Required:

  • A Master’s degree in Chemistry
  • Experience in organic synthesis
  • Good communication skills in English

Key personal characteristics:

  •  Driven by curiosity, enthusiasm and persistence, combined with a desire to learn
  • Commitment to actively participate and promote a positive lab environment

We offer

  • Access to, and training on, state-of-the-art research facilities within the Stratingh Institute for Chemistry
  • An open and supportive research environment
  • A fully funded position

We look forward to receiving your application with the following documents:

  • A letter stating your motivation to apply and your key qualities relevant for this position.
  •  A curriculum vitae.
  • Contact information of two academic references.

You may apply for this position until 15 November 11:59 pm / before 16
November 2024 Dutch local time (CET) by means of the electronic application
form (click on “Apply below” on the advertisement on the University website)