April 21, 2020
On short notice we are looking for a postdoc in the field of natural product synthesis. The project comprises the total synthesis of mycolic acids, complex lipids originating from M. tuberculosis. In the group we have developed a first generation synthesis of these compounds. In a collaboration with the Tetramer Facility of the National Institute of Health (Emory University, USA), mycolic acids will be loaded on antigen-presenting proteins in order to identify reactive T-cells. Therefore the mycolic acid need to be prepared in larger quantities and the synthesis reworked/streamlined. In addition there is room for additional research in natural product synthesis. The project, initially for one year, is funded by the NIH.
The candidate should have a track record in (natural product) synthesis. Due to the short notice, candidates must be eligible to work in The Netherlands on the date of application. Applications should be sent to A.J.Minnaard@rug.nl